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Abdominal aortic aneurysms (AAA) are associated with systemic inflammation and endothelial dysfunction. We previously reported flow mediated dilatation (FMD) of the brachial artery as a predictor of AAA growth. We hence hypothesised that other physical characteristics of the brachial artery correlate with AAA growth. Using a prospectively cohort of AAA patients, we devised a 'brachial artery relaxation index' (BARI) and examined its role as a biomarker for AAA growth. However, no correlation between BARI and future aneurysm growth was observed (p = 0.45). Therefore, our investigations did not substantiate the hypothesis that other physical characteristics of the brachial artery predicts AAA growth.

Original publication

DOI

10.1371/journal.pone.0248043

Type

Journal article

Journal

PLoS One

Publication Date

2021

Volume

16

Keywords

Aged, Aortic Aneurysm, Abdominal, Brachial Artery, Female, Humans, Male, Prognosis, Prospective Studies, Ultrasonography